Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | F7 | P08709 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27820730 | 0.88 | F2 (0.53) | ALDH1A1KDM4EPOLBL3MBTL1F2 | |
| SCHEMBL5552677 | 0.85 | F2 (0.51) | ALDH1A1KDM4EPOLBL3MBTL1F2 | |
| SCHEMBL965193 | 0.82 | F2 (0.49) | ALDH1A1KDM4EPOLBL3MBTL1F2 | |
| SCHEMBL965192 | 0.82 | F2 (0.49) | ALDH1A1KDM4EPOLBL3MBTL1F2 | |
| SCHEMBL6874912 | 0.82 | HPGD (0.51) | ALDH1A1KDM4EPOLBF2F7 | |
| SCHEMBL10477773 | 0.81 | L3MBTL1 (0.43) | ALDH1A1KDM4EPOLBL3MBTL1F2 | |
| SCHEMBL852240 | 0.80 | ALDH1A1 (0.59) | ALDH1A1KDM4EPOLBL3MBTL1FOLH1 | |
| SCHEMBL5702073 | 0.80 | FFAR4 (0.50) | ALDH1A1KDM4EPOLBL3MBTL1FOLH1 | |
| SCHEMBL4416634 | 0.80 | FOLH1 (0.58) | ALDH1A1KDM4EPOLBL3MBTL1FOLH1 | |
| SCHEMBL5431545 | 0.79 | LRRK2 (0.63) | ALDH1A1KDM4EPOLBL3MBTL1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101239969-B | Biphenyl derivatives | THERAVANCE INC | 2011-07-20 | — | — | CN | disclosed |
| CN-101239968-B | Biphenyl derivatives | THERAVANCE INC | 2011-07-20 | — | — | CN | disclosed |
| CN-101239970-B | Biphenyl derivatives | THERAVANCE INC | 2011-07-20 | — | — | CN | disclosed |
| CN-101239971-B | Biphenyl derivatives | THERAVANCE INC | 2011-07-20 | — | — | CN | disclosed |
| CN-101239968-A | Biphenyl derivatives | THERAVANCE INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101239969-A | Biphenyl derivatives | THERAVANCE INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101239971-A | Biphenyl derivatives | THERAVANCE INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-101239970-A | Biphenyl derivatives | THERAVANCE INC (US) | 2008-08-13 | — | — | CN | disclosed |
| CN-100378092-C | Biphenyl derivatives | THERAVANCE INC (US) | 2008-04-02 | — | — | CN | disclosed |
| CN-1759108-A | Biphenyl derivatives | THERAVANCE INC (US) | 2006-04-12 | — | — | CN | disclosed |