Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.42 |
| ▸ | WNT3A | P56704 | 3/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628166 | 0.78 | KDM4E (0.47) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL8283151 | 0.74 | GAA (0.50) | KMT2ACYP2C19ALDH1A1POLBMEN1 | |
| SCHEMBL20559094 | 0.72 | CES2 (0.45) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL2761658 | 0.71 | KDM4E (0.43) | KMT2AALDH1A1NPSR1MEN1SMN1; SMN2 | |
| SCHEMBL253276 | 0.70 | CES2 (0.64) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL2470002 | 0.70 | CTNNB1 (0.71) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL29355245 | 0.70 | CES2 (0.64) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL9493294 | 0.70 | LMNA (0.61) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL23354036 | 0.69 | LMNA (0.55) | L3MBTL1LMNANAPRTP4HTMCES2 | |
| SCHEMBL2418294 | 0.69 | CTNNB1 (0.55) | L3MBTL1LMNANAPRTP4HTMCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010149888-A1 | DERIVATIVES OF 2-MERCAPTOCYCLOPENTANE CARBOXYLIC ACID, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | LES LABORATOIRES SERVIER (FR) | 2010-12-29 | — | — | WO | disclosed |