SCHEMBL253276

SCHEMBL253276

O=C(CC(=O)c1ccccn1)c1ccccn1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.64
CES1 P23141 1/20 0.64
L3MBTL1 Q9Y468 2/20 0.61
LMNA P02545 1/20 0.61
NAPRT Q6XQN6 1/20 0.61
P4HTM Q9NXG6 1/20 0.61
ALDH1A1 P00352 1/20 0.59
CTNNB1 P35222 5/20 0.58
WNT3A P56704 3/20 0.56
GRM4 Q14833 1/20 0.56
KMT2A Q03164 2/20 0.55
GSK3B P49841 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
GRM5 P41594 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC4 P56524 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC10 Q969S8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355245 1.00 CES2 (0.64) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL33721999 0.91 CES2 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL2544523 0.91 CES2 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL4625845 0.90 KMT2A (0.63) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL9493294 0.90 LMNA (0.61) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL5159751 0.88 CES2 (0.55) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL1360847 0.88 ALDH1A1 (0.62) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL29740682 0.88 ALDH1A1 (0.62) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL2470002 0.86 CTNNB1 (0.71) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL30534787 0.86 ALDH1A1 (0.60) CES2CES1L3MBTL1LMNANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 207 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240093086-A1 HYDROPHIBIC CARBON-DOTS FOR OIL TRACERS ARAMCO SERVICES COMPANY (US) 2024-03-21 US claimed
US-20230406990-A1 REACTIVE COMPOUND FOR PRODUCING POLYURETHANE LAYERS HAVING THERMALLY ACTIVATABLE CATALYST SYSTEMS BENECKE-KALIKO AG (DE) 2023-12-21 US claimed
EP-4214255-A1 REACTIVE COMPOUND FOR PRODUCING POLYURETHANE LAYERS HAVING THERMALLY ACTIVATABLE CATALYST SYSTEMS Benecke-Kaliko AG (DE) 2023-07-26 EP claimed
CN-116096772-A Reactive mixtures for producing polyurethane layers with heat-activatable catalyst systems 贝内克-凯利科股份公司 2023-05-09 CN claimed
WO-2022057985-A1 REACTIVE COMPOUND FOR PRODUCING POLYURETHANE LAYERS HAVING THERMALLY ACTIVATABLE CATALYST SYSTEMS BENECKE-KALIKO AG (DE) 2022-03-24 WO claimed
US-12570771-B2 Curing catalyst used for curing of polymer, production method for said curing catalyst, mositure-curable composition, and production method for cured product NITTO KASEI CO., LTD. (JP) 2026-03-10 US disclosed
EP-4682204-A1 CURABLE COMPOSITION Kaneka Corporation (JP) 2026-01-21 EP disclosed
US-12522591-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2026-01-13 US disclosed
US-12516157-B2 Curing catalyst used for curing polymer, method for producing same, moisture-curable composition, and method for producing cured product NITTO KASEI CO., LTD. (JP) 2026-01-06 US disclosed
US-12514107-B2 Organic electroluminescent apparatus MERCK PATENT GMBH (DE) 2025-12-30 US disclosed
EP-4180482-B1 MOISTURE-CURABLE COMPOSITION NITTO KASEI CO LTD (JP) 2025-12-03 EP disclosed
EP-4656672-A1 METHOD FOR PRODUCING CURABLE COMPOSITION Kaneka Corporation (JP) 2025-12-03 EP disclosed
WO-2011051540-A1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORPORATION (FI) 2011-05-05 WO disclosed
US-7880013-B2 Thiazole derivatives KYOWA HAKKO KIRIN CO., LTD. (JP) 2011-02-01 US disclosed
US-20100256361-A1 THIAZOLE DERIVATIVES KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-10-07 US disclosed
US-7718808-B2 Thiazole derivatives KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-05-18 US disclosed
US-20070132366-A1 Light emitting device and lighting device using it, image display unit MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-14 US disclosed
US-20070132366-A1 Light emitting device and lighting device using it, image display unit MITSUBISHI CHEMICAL CORPORATION (JP) 2007-06-14 US disclosed
US-20070105919-A1 adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders KYOWA HAKKO KOGYO CO., LTD. (JP) 2007-05-10 US disclosed
EP-1700856-A1 THIAZOLE DERIVATIVE KYOWA HAKKO KOGYO CO., LTD. (JP) 2006-09-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570771-B2 Curing catalyst used for curing of polymer, production method for said curing catalyst, mositure-curable composition, and production method for cured product RPS6KB1, RPS6KA1, RPS6KB2 CES2 1603/4885CES1 697/4885L3MBTL1 2074/4885
US-20100256361-A1 THIAZOLE DERIVATIVES ADORA2A, ADORA3, ADORA1 CES2 798/4885CES1 1610/4885L3MBTL1 2618/4885
US-12514107-B2 Organic electroluminescent apparatus SCO2, RIF1, RER1 CES2 2137/4885CES1 3863/4885L3MBTL1 1903/4885
US-20070105919-A1 adenosine A2A receptor antagonists; N-[4-(2-Furyl)-5-(4-pyridyl)thiazol-2-yl]pyridine-4-carboxamide; treatment of Parkinson's disease, Alzheimer's disease, progressive supranuclear palsy, AIDS encephalopathy, nerve system disorders ADORA2A, ADORA3, ADORA1 CES2 1189/4885CES1 3277/4885L3MBTL1 2473/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.