Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28788244 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL5658223 | 0.82 | L3MBTL1 (0.45) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL28279066 | 0.79 | KDM4E (0.46) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL29508482 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL20558075 | 0.74 | GRM4 (0.49) | ALDH1A1CYP3A4TDP1TSHRKDM4E | |
| SCHEMBL14931471 | 0.74 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL7820375 | 0.73 | ALDH1A1 (0.42) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| Hydrochloric Acid SCHEMBL28196297 | 0.72 | CYP3A4 (0.56) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL2380637 | 0.71 | CYP3A4 (0.54) | ALDH1A1CYP3A4TDP1HPGDTSHR | |
| SCHEMBL31339851 | 0.71 | CYP3A4 (0.54) | ALDH1A1CYP3A4TDP1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102316869-A | The treatment method for cancer | AMC AMSTERDAM | 2012-01-11 | — | — | CN | claimed |
| CN-105384827-A | Chimeric endonucleases and uses thereof | BASF PLANT SCIENCE CO GMBH | 2016-03-09 | — | — | CN | disclosed |
| CN-102686726-B | Chimeric endonucleases and uses thereof | BASF PLANT SCIENCE Co.,GmbH (DE) | 2015-12-16 | — | — | CN | disclosed |
| CN-102388307-B | Diagnosis of multiple sclerosis | YEDA RES & DEV | 2014-09-03 | — | — | CN | disclosed |
| CN-101137752-B | Intron sequence for enhancing expression | BASF PLANT SCIENCE GMBH | 2013-04-03 | — | — | CN | disclosed |
| CN-102925479-A | Expression enhancing intron sequences | BASF PLANT SCIENCE GMBH | 2013-02-13 | — | — | CN | disclosed |
| CN-102762726-A | Chimeric endonucleases and uses thereof | BASF PLANT SCIENCE CO GMBH | 2012-10-31 | — | — | CN | disclosed |
| CN-102725412-A | Optimized endonucleases and uses thereof | BASF PLANT SCIENCE CO GMBH | 2012-10-10 | — | — | CN | disclosed |
| CN-102686726-A | Chimeric endonucleases and uses thereof | BASF PLANT SCIENCE CO GMBH | 2012-09-19 | — | — | CN | disclosed |
| CN-102388307-A | Diagnosis of multiple sclerosis | YEDA RES & DEV | 2012-03-21 | — | — | CN | disclosed |
| CN-102316869-A | The treatment method for cancer | AMC AMSTERDAM | 2012-01-11 | — | — | CN | disclosed |
| CN-101678002-A | Methods of treatment using intravenous formulations comprising temozolomide | SCHERING CORP | 2010-03-24 | — | — | CN | disclosed |
| CN-100451123-C | Recombination systems and a method for removing nucleic acid sequences from the genome of eukaryotic organisms | SUNGENE GMBH & CO KGAA (DE) | 2009-01-14 | — | — | CN | disclosed |
| CN-101137752-A | Intron sequence for enhancing expression | BASF PLANT SCIENCE GMBH (DE) | 2008-03-05 | — | — | CN | disclosed |
| CN-100364438-C | Use of astaxanthin-containing plants or parts of plants of the genus tagetes as animal feed | SUNGENE GMBH & CO KGAA (DE) | 2008-01-30 | — | — | CN | disclosed |
| CN-101098696-A | Improved dosing regimen of temozolomide for treating cancer based on the patient's mgmt level | SCHERING CORP (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1688712-A | Method for producing ketocarotenoids in flowers of plants | SUNGENE GMBH & CO KGAA (DE) | 2005-10-26 | — | — | CN | disclosed |
| CN-1688206-A | Use of astaxanthin-containing plants or parts of plants of the genus tagetes as animal feed | SUNGENE GMBH & CO KGAA (DE) | 2005-10-26 | — | — | CN | disclosed |
| CN-1628174-A | Recombination systems and a method for removing nucleic acid sequences from the genome of eukaryotic organisms | SUNGENE GMBH & CO KGAA (DE) | 2005-06-15 | — | — | CN | disclosed |