Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IAPP | P10997 | 4/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL860002 | 0.82 | TAAR1 (0.57) | TAAR1AKR1B1NPC1PKMRAB9A | |
| Salicyl Alcohol SCHEMBL8589411 | 0.77 | HSPA5 (0.41) | TAAR1AKR1B1RAB9AHRH3HSPA5 | |
| SCHEMBL9321175 | 0.71 | MTNR1A (0.47) | IAPPMTNR1AMPOALDH1A1 | |
| SCHEMBL30203505 | 0.69 | IAPP (0.68) | TAAR1AKR1B1IAPPMTNR1AMPO | |
| SCHEMBL11751573 | 0.68 | IAPP (0.59) | TAAR1AKR1B1NPC1PKMRAB9A | |
| SCHEMBL29373796 | 0.66 | AKR1B1 (0.65) | TAAR1AKR1B1NPC1PKMRAB9A | |
| SCHEMBL35529 | 0.66 | AKR1B1 (0.65) | TAAR1AKR1B1NPC1PKMRAB9A | |
| SCHEMBL7128255 | 0.66 | AKR1B1 (0.65) | TAAR1AKR1B1NPC1PKMRAB9A | |
| SCHEMBL8967245 | 0.65 | CYP4F2 (0.43) | MTNR1AMPO | |
| SCHEMBL269353 | 0.65 | IAPP (0.72) | TAAR1AKR1B1NPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100341496-C | Agent for preventing or treating kidney disease | KISSEI PHARMACEUTICAL (JP) | 2007-10-10 | — | — | CN | disclosed |
| CN-1652761-A | Agent for preventing or treating kidney disease | KISSEI PHARMACEUTICAL (JP) | 2005-08-10 | — | — | CN | disclosed |