Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 3/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321175 | 0.87 | MTNR1A (0.47) | IAPPMPOKDM4EALDH1A1MTNR1A | |
| SCHEMBL30203505 | 0.84 | IAPP (0.68) | TAAR1AKR1B1IAPPMPOALDH1A1 | |
| SCHEMBL11751573 | 0.83 | IAPP (0.59) | TAAR1AKR1B1HSPA5IAPPMPO | |
| SCHEMBL35529 | 0.81 | AKR1B1 (0.65) | TAAR1AKR1B1HSPA5IAPPMPO | |
| SCHEMBL29373796 | 0.81 | AKR1B1 (0.65) | TAAR1AKR1B1HSPA5IAPPMPO | |
| SCHEMBL7128255 | 0.81 | AKR1B1 (0.65) | TAAR1AKR1B1HSPA5IAPPMPO | |
| Methane SCHEMBL1275762 | 0.79 | AKR1B1 (0.63) | TAAR1AKR1B1HSPA5IAPPMPO | |
| SCHEMBL269353 | 0.79 | IAPP (0.72) | TAAR1AKR1B1HSPA5IAPPMPO | |
| SCHEMBL8967245 | 0.79 | CYP4F2 (0.43) | MPOKDM4EMTNR1A | |
| SCHEMBL29934495 | 0.79 | IAPP (0.72) | TAAR1AKR1B1HSPA5IAPPMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166841-A1 | Improved Performance of Carbon Nanotube Based Polymeric Materials | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2024-05-23 | — | — | US | disclosed |
| WO-2023244831-A1 | IRON COMPLEXES AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2023-12-21 | — | — | WO | disclosed |
| US-11725075-B2 | Thermoplastic polyurethane | BASF SE (DE) | 2023-08-15 | — | — | US | disclosed |
| US-11535697-B2 | Thermoplastic polyurethane | BASF SE (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20220033566-A1 | THERMOPLASTIC POLYURETHANE | BASF SE (DE) | 2022-02-03 | — | — | US | disclosed |
| US-10941429-B2 | Enzymatic synthesis of kavalactones and flavokavains | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2021-03-09 | — | — | US | disclosed |
| US-10723753-B2 | Ras inhibitors and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| US-20200231739-A1 | THERMOPLASTIC POLYURETHANE | BASF SE (DE) | 2020-07-23 | — | — | US | disclosed |
| US-20200223863-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | UNIV CALIFORNIA (US) | 2020-06-18 | — | — | US | disclosed |
| EP-0968076-A1 | PROCESS FOR CONTINUOUSLY PRODUCING POLYESTER ARTICLES WITH SCRAP RECYCLE IN A CONTINUOUS MELT-TO-PREFORM PROCESS | EASTMAN CHEMICAL COMPANY (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999052903-A1 | PRODRUGS OF BENZOFURANYLMETHYL CARBAMATE NK1 ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1999-10-21 | — | — | WO | disclosed |
| US-5817529-A | HAPTENS, ANTIGENS, IMMUNOASSAY, LABELS | ROCHE DIAGNOSTIC SYSTEMS, INC. (US) | 1998-10-06 | — | — | US | disclosed |
| WO-1998041375-A1 | PROCESS FOR CONTINUOUSLY PRODUCING POLYESTER ARTICLES WITH SCRAP RECYCLE IN A CONTINUOUS MELT-TO-PREFORM PROCESS | EASTMAN CHEMICAL COMPANY (US) | 1998-09-24 | — | — | WO | disclosed |
| WO-1998041559-A1 | PROCESS FOR THE MODIFICATION OF A POLYESTER MELT USED IN A CONTINUOUS MELT-TO-PREFORM PROCESS | EASTMAN CHEMICAL COMPANY (US) | 1998-09-24 | — | — | WO | disclosed |
| US-5672584-A | MODIFIED WITH END GROUPS | THE UNIVERSITY OF KANSAS (US) | 1997-09-30 | — | — | US | disclosed |
| EP-0558959-B1 | Phosphonooxy and carbonate derivatives of taxol | BRISTOL MYERS SQUIBB CO (US) | 1997-04-16 | — | — | EP | disclosed |
| EP-0747707-A1 | Propoxyphene derivatives for immunoassay reagents | F. HOFFMANN-LA ROCHE AG (CH) | 1996-12-11 | — | — | EP | disclosed |
| US-5272171-A | Phosphonooxy and carbonate derivatives of taxol | BRISTOL-MYERS SQUIBB COMPANY (US) | 1993-12-21 | — | — | US | disclosed |
| EP-0558959-A1 | Phosphonooxy and carbonate derivatives of taxol | Bristol-Myers Squibb Company (US) | 1993-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200223863-A1 | SYNTHESIS OF HALICHONDRIN ANALOGS AND USES THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, KIF5C, KIF23 | TAAR1 4779/4885AKR1B1 565/4885HSPA5 825/4885 |
| US-20200188476-A1 | ANTI-MICROBIAL AGENT-POLYMER CONJUGATES AND METHODS OF USE THEREOF | DDOST, MGAM, MSN | TAAR1 4677/4885AKR1B1 4345/4885HSPA5 1614/4885 |
| US-10723753-B2 | Ras inhibitors and uses thereof | KRAS, NRAS, RASGRP1 | TAAR1 4121/4885AKR1B1 1391/4885HSPA5 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.