Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711947 | 0.78 | KDM4E (0.47) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL7567713 | 0.74 | ALDH1A1 (0.44) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL21062093 | 0.73 | KMT2A (0.42) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL28249694 | 0.71 | — | — | |
| SCHEMBL1486024 | 0.68 | APEX1 (0.44) | KMT2AAKR1B10AKR1B1APEX1MEN1 | |
| SCHEMBL6280747 | 0.67 | KDM4E (0.45) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL1280773 | 0.67 | TSHR (0.56) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL3581778 | 0.67 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL3590708 | 0.67 | ALDH1A1 (0.43) | KMT2AALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL20541532 | 0.67 | HDAC6 (0.45) | KMT2AALDH1A1MAPTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109369625-A | A kind of ortho esters 5 FU 5 fluorouracil prodrugs, preparation method and its acid-sensitive nanoparticle and application | 安徽大学 | 2019-02-22 | — | — | CN | claimed |
| CN-107892686-A | A kind of genistein derivative and its preparation method and application | 荆楚理工学院 | 2018-04-10 | — | — | CN | claimed |
| CN-100588428-C | Fluorouracil-dextran and process for preparing the same | UNIV SHENYANG PHARMACEUTICAL | 2010-02-10 | — | — | CN | claimed |
| CN-1733312-A | Fluorouracil-dextran and process for preparing the same | UNIV SHENYANG PHARMACEUTICAL (CN) | 2006-02-15 | — | — | CN | claimed |
| CN-109369625-A | A kind of ortho esters 5 FU 5 fluorouracil prodrugs, preparation method and its acid-sensitive nanoparticle and application | 安徽大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-107892686-A | A kind of genistein derivative and its preparation method and application | 荆楚理工学院 | 2018-04-10 | — | — | CN | disclosed |
| CN-100588428-C | Fluorouracil-dextran and process for preparing the same | UNIV SHENYANG PHARMACEUTICAL | 2010-02-10 | — | — | CN | disclosed |
| CN-1733312-A | Fluorouracil-dextran and process for preparing the same | UNIV SHENYANG PHARMACEUTICAL (CN) | 2006-02-15 | — | — | CN | disclosed |