Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062093 | 0.85 | KMT2A (0.42) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL11711947 | 0.77 | KDM4E (0.47) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL27422651 | 0.75 | MAPK14 (0.47) | ALDH1A1KDM4EPOLBKMT2AMEN1 | |
| SCHEMBL27619838 | 0.74 | KMT2A (0.43) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL6280747 | 0.70 | KDM4E (0.45) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL3581778 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL3590708 | 0.67 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL4591705 | 0.67 | KDM4E (0.56) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL11644757 | 0.66 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EPOLBKMT2A | |
| SCHEMBL27757531 | 0.65 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972707-B | Treatment of conditions involving demyelination | BIOGEN IDEC INC | 2014-12-03 | — | — | CN | disclosed |
| CN-1622995-B | Novel receptor nucleic acids and polypeptides | BIOGEN IDEC INC | 2013-09-04 | — | — | CN | disclosed |
| CN-101925612-A | Antibodies against epitopes of cancer-associated NFKBIB variants and uses thereof | VIVENTIA BIOTECH INC | 2010-12-22 | — | — | CN | disclosed |
| CN-101014245-A | Taj in neuronal function | BIOGEN IDEC INC (US) | 2007-08-08 | — | — | CN | disclosed |
| CN-101001606-A | Preventing skin damage | GEN HOSPITAL CORP (US) | 2007-07-18 | — | — | CN | disclosed |
| CN-1972707-A | Treatment of conditions involving demyelination | BIOGEN IDEC INC (US) | 2007-05-30 | — | — | CN | disclosed |
| CN-1940068-A | Novel receptor nucleic acids and polypeptides | BIOGEN IDEC INC (US) | 2007-04-04 | — | — | CN | disclosed |
| CN-1622995-A | Novel receptor nucleic acids and polypeptides | BIOGEN (US) | 2005-06-01 | — | — | CN | disclosed |
| WO-2002079411-A2 | MICROARRAY GENE EXPRESSION PROFILING IN CLEAR CELL RENAL CELL CARCINOMA: PROGNOSIS AND DRUG TARGET IDENTIFICATION | VAN ANDEL INSTITUTE (US) | 2002-10-10 | — | — | WO | disclosed |
| CN-1306576-A | G-beta-gamma regulated phosphatidylinositol-3' kinase | ONYX PHARMA INC (US) | 2001-08-01 | — | — | CN | disclosed |