Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.47 |
| ▸ | ARG1 | P05089 | 2/20 | 0.43 |
| ▸ | ARG2 | P78540 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | ODC1 | P11926 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1816172 | 1.00 | GGT1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL19940213 | 0.84 | GGT1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27620451 | 0.83 | ACE2 (0.44) | GGT1ARG1ARG2BLMCA2 | |
| SCHEMBL1816887 | 0.82 | GGT1 (0.48) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27601869 | 0.82 | GGT1 (0.48) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL4332705 | 0.81 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27598551 | 0.81 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27620484 | 0.81 | GGT1 (0.44) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL7281147 | 0.79 | GGT1 (0.41) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL4291015 | 0.79 | GGT1 (0.50) | GGT1ARG1ARG2NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-103702995-B | 4-{ [4-({ [4-(2,2,2-trifluoro ethoxy)-1,2-benzoisoxazole-3-base] oxygen } methyl) piperidin-1-yl] methyl } polymorphic forms of-tetrahydrochysene-2H-pyrans-4-carboxylic acid | RAQUALIA PHARMA INC. (JP) | 2016-04-13 | — | — | CN | disclosed |
| CN-105164129-A | Polymorph forms | RAQUALIA PHARMA INC | 2015-12-16 | — | — | CN | disclosed |
| CN-103702995-A | Polymorph form of 4-{[4-({[4-(2,2,2-trifluoroethoxy)-1,2-benzisoxazol-3-yl]oxy}methyl)piperidin-1-yl]methyl}-tetrahydro-2h-pyran-4-carboxylic acid | RAQUALIA PHARMA INC | 2014-04-02 | — | — | CN | disclosed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |