Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.50 |
| ▸ | ARG1 | P05089 | 2/20 | 0.46 |
| ▸ | ARG2 | P78540 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332705 | 0.84 | GGT1 (0.52) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL27598551 | 0.84 | GGT1 (0.52) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL27414068 | 0.80 | ACACB (0.35) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL19940213 | 0.79 | GGT1 (0.47) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL27620482 | 0.79 | GGT1 (0.47) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL1816172 | 0.79 | GGT1 (0.47) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL28943929 | 0.78 | GGT1 (0.50) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL8687592 | 0.78 | GGT1 (0.65) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL497269 | 0.77 | GGT1 (0.43) | GGT1ARG1ARG2ACACBACACA | |
| SCHEMBL1816887 | 0.77 | GGT1 (0.48) | GGT1ARG1ARG2ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329926-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-20090012037-A1 | Antiviral Compounds | GILEAD SCIENCE, INC. (US) | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012037-A1 | Antiviral Compounds | EIF2AK2, MAVS, ITPA | GGT1 1391/4885ARG1 3649/4885ARG2 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.