Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.52 |
| ▸ | ARG1 | P05089 | 2/20 | 0.47 |
| ▸ | ARG2 | P78540 | 2/20 | 0.47 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | ACACA | Q13085 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27598551 | 1.00 | GGT1 (0.52) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL4291015 | 0.84 | GGT1 (0.50) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27620495 | 0.84 | ARG1 (0.55) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27620423 | 0.83 | GGT1 (0.42) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL19975107 | 0.82 | BLM (0.53) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL27620482 | 0.81 | GGT1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL1816172 | 0.81 | GGT1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL19940213 | 0.81 | GGT1 (0.47) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL28943929 | 0.80 | GGT1 (0.50) | GGT1ARG1ARG2NOS2NOS1 | |
| SCHEMBL8687592 | 0.80 | GGT1 (0.65) | GGT1ARG1ARG2NOS2NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612226-B2 | Amino acid derivatives | PFIZER INC. (US) | 2009-11-03 | — | — | US | disclosed |
| EP-1879567-A1 | AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-01-23 | — | — | EP | disclosed |
| US-20060247291-A1 | Amino acid derivatives | PFIZER, INC. | 2006-11-02 | — | — | US | disclosed |
| WO-2006114707-A1 | AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247291-A1 | Amino acid derivatives | OPRL1, BCAT2, BCAT1 | GGT1 1955/4885ARG1 18/4885ARG2 109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.