Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGT1 | P19440 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.42 |
| ▸ | ARG1 | P05089 | 1/20 | 0.42 |
| ▸ | ARG2 | P78540 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27620442 | 0.98 | GGT1 (0.47) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL27620501 | 0.94 | GGT1 (0.47) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL4335456 | 0.90 | GGT1 (0.50) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL27602074 | 0.90 | GGT1 (0.50) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL3614328 | 0.82 | GRM2 (0.51) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL3614325 | 0.82 | GRM2 (0.51) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL8957923 | 0.82 | GRM2 (0.51) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL27601891 | 0.82 | METAP1 (0.41) | GGT1GRM2GRM3ARG1ARG2 | |
| SCHEMBL7519834 | 0.80 | ALDH1A1 (0.40) | HPGDEPHX1SIGMAR1SMN1; SMN2HSD17B10 | |
| SCHEMBL14923381 | 0.80 | HPGD (0.39) | HPGDCYP1A2CYP2D6METAP1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |