Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | ARG2 | P78540 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27601841 | 0.98 | BLM (0.36) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27658553 | 0.95 | GGT1 (0.36) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27620516 | 0.83 | GGT1 (0.41) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27620535 | 0.81 | GGT1 (0.42) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27601860 | 0.77 | GGT1 (0.42) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL28755085 | 0.76 | GGT1 (0.38) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27602082 | 0.74 | ARG1 (0.35) | BLMUSP2ALDH1A1CYP1A2GGT1 | |
| Urea SCHEMBL1835225 | 0.72 | ALDH1A1 (0.45) | BLMUSP2ALDH1A1LMNACYP1A2 | |
| SCHEMBL27601835 | 0.72 | GGT1 (0.38) | BLMUSP2ALDH1A1CYP1A2GGT1 | |
| SCHEMBL27601825 | 0.71 | GGT1 (0.35) | BLMGGT1ARG1ARG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | claimed |
| CN-100462351-C | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2009-02-18 | — | — | CN | disclosed |
| CN-1856301-A | Curable beta-amino acid | WARNER LAMBERT CO (US) | 2006-11-01 | — | — | CN | disclosed |
| CN-1817854-A | Amino acids with affinity for the alpha-2-delta protein | WARNER LAMBERT CO (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1653036-A | Amino acids having affinity for the alpha 2 delta protein | WARNER LAMBERT CO (US) | 2005-08-10 | — | — | CN | disclosed |