Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 17/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 16/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 16/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 16/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408833 | 0.81 | HDAC4 (0.44) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL15529338 | 0.78 | OPRL1 (0.42) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL29262368 | 0.77 | HDAC4 (0.43) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL28854800 | 0.76 | AKR1B1 (0.47) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL28444682 | 0.74 | OPRL1 (0.56) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL1493256 | 0.72 | KMT2A (0.42) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL19205451 | 0.72 | ALDH1A1 (0.43) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL28994161 | 0.71 | OPRM1 (0.56) | OPRL1OPRM1OPRD1OPRK1HDAC4 | |
| SCHEMBL21587746 | 0.69 | OPRL1 (0.44) | OPRL1OPRM1OPRD1OPRK1SIGMAR1 | |
| SCHEMBL17353520 | 0.69 | OPRL1 (0.41) | OPRL1OPRM1OPRD1OPRK1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1662241-A | Use of cyclic thiocarbamate derivatives in the treatment of hormone-related disorders | WYETH CORP (US) | 2005-08-31 | — | — | CN | disclosed |