Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27603916 | 0.83 | SCN9A (0.34) | ALDH1A1APLNRSPR | |
| SCHEMBL5831699 | 0.83 | HSD11B1 (0.44) | ALDH1A1L3MBTL1ENPP2MAPK1HSD17B10 | |
| SCHEMBL5830894 | 0.83 | KMT2A (0.41) | ALDH1A1L3MBTL1ENPP2GLSKMT2A | |
| SCHEMBL5831423 | 0.82 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1ENPP2MAPK1HSD17B10 | |
| SCHEMBL5831576 | 0.81 | HSD11B1 (0.46) | ALDH1A1L3MBTL1 | |
| SCHEMBL5830665 | 0.79 | HSD11B1 (0.39) | ALDH1A1L3MBTL1ENPP2APLNRGLS | |
| SCHEMBL5831015 | 0.77 | CA1 (0.54) | ALDH1A1L3MBTL1MAPK1KMT2ASMN1; SMN2 | |
| SCHEMBL5831631 | 0.77 | AADAT (0.45) | ALDH1A1L3MBTL1HSD17B10PKMKMT2A | |
| SCHEMBL5831583 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PKMKMT2ASMN1; SMN2RECQL | |
| SCHEMBL6623399 | 0.76 | HSD11B1 (0.45) | ALDH1A1GLSATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | claimed |
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | disclosed |