SCHEMBL27622679

SCHEMBL27622679

CCOC(=O)CCC(=O)OC1CCCCC1C(C)C

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
CYP2D6 P10635 1/20 0.39
LMNA P02545 2/20 0.37
NAAA Q02083 2/20 0.36
KMT2A Q03164 2/20 0.36
EPHX1 P07099 2/20 0.35
TRPM8 Q7Z2W7 1/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 2/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CYP19A1 P11511 2/20 0.34
SMYD3 Q9H7B4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19690601 0.91 ALDH1A1 (0.40) ALDH1A1LMNANAAAKMT2AEPHX1
SCHEMBL19690602 0.84 LMNA (0.46) ALDH1A1LMNANAAAKMT2AEPHX1
SCHEMBL16281717 0.84 ALDH1A1 (0.35) ALDH1A1LMNANAAAKMT2AEPHX1
SCHEMBL27622673 0.77 ALDH1A1 (0.43) ALDH1A1CYP2D6LMNANAAAKMT2A
SCHEMBL27182991 0.76 CYP19A1 (0.52) ALDH1A1LMNAKMT2AEPHX1TRPM8
SCHEMBL27823806 0.76 NAAA (0.36) ALDH1A1CYP2D6LMNANAAAKMT2A
SCHEMBL20857700 0.75 NAAA (0.61) ALDH1A1CYP2D6LMNANAAAKMT2A
SCHEMBL27622689 0.75 NAAA (0.38) ALDH1A1CYP2D6LMNANAAAKMT2A
SCHEMBL13558208 0.74 EPHX1 (0.40) ALDH1A1KMT2AEPHX1TRPM8MEN1
SCHEMBL13515570 0.74 EPHX1 (0.40) ALDH1A1KMT2AEPHX1TRPM8MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102781970-B Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA S.R.L. (IT) 2015-08-12 CN disclosed
CN-104768980-A Broad molecular weight distribution polypropylene resins EXXONMOBIL CHEM PATENTS INC 2015-07-08 CN disclosed
CN-104479055-A Dialkoxymagnesium support type solid catalyst component and catalyst RENQIU LIHE TECHNOLOGY DEV CO LTD 2015-04-01 CN disclosed
CN-104109212-A Solid catalyst component used for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-10-22 CN disclosed
CN-104045748-A Solid catalyst component for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY LTD 2014-09-17 CN disclosed
CN-102643370-B Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE SPA 2014-08-13 CN disclosed
CN-103936892-A Solid catalyst component for olefin polymerization and catalyst BEIJIG LIHE ZHIXIN TECHNOLOGY LTD 2014-07-23 CN disclosed
CN-103923238-A Catalyst component for olefin polymerization and catalyst BEIJING LIHE ZHIXIN TECHNOLOGY CO LTD 2014-07-16 CN disclosed
CN-103476806-A Catalyst components for the polymerization of olefins BASELL POLIOLEFINE SRL 2013-12-25 CN disclosed
CN-102781970-A Catalyst components for the polymerization of olefins BASELL POLIOLEFINE ITALIA SRL 2012-11-14 CN disclosed
CN-102643370-A Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE SPA 2012-08-22 CN disclosed
CN-101065437-B Elastomeric polyolefin compositions BASELL POLIOLEFINE SRL 2010-12-08 CN disclosed
CN-100523076-C Impact resistant polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2009-08-05 CN disclosed
CN-101065437-A Elastomeric polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2007-10-31 CN disclosed
CN-1768108-A Impact resistant polyolefin compositions BASELL POLIOLEFINE SRL (IT) 2006-05-03 CN disclosed
CN-1681853-A Components and catalysts for the polymerization of olefins BASELL POLIOLEFINE SPA (IT) 2005-10-12 CN disclosed