Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.35 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | IRS1 | P35568 | 2/20 | 0.34 |
| ▸ | GAB1 | Q13480 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27622999 | 0.91 | KMT2A (0.36) | KMT2AMEN1POLBKLKB1CTSB | |
| SCHEMBL27622676 | 0.89 | ALDH1A1 (0.37) | KMT2AMEN1POLBKLKB1CTSB | |
| SCHEMBL28755208 | 0.83 | HSD11B1 (0.38) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL27564639 | 0.83 | HSD11B1 (0.55) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL5831426 | 0.81 | KMT2A (0.45) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL5831400 | 0.77 | KMT2A (0.42) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL27538737 | 0.74 | KMT2A (0.46) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL27622959 | 0.74 | NPC1 (0.35) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 | |
| SCHEMBL28755292 | 0.72 | NPC1 (0.36) | KMT2AMEN1LMNAALDH1A1HTT | |
| SCHEMBL27534026 | 0.72 | CTPS1 (0.47) | KMT2AHSD11B1HSD17B1HSD17B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | claimed |
| CN-1649855-A | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | BIOVITRUM AB (SE) | 2005-08-03 | — | — | CN | disclosed |