Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 6/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27604008 | 0.80 | SLC18A3 (0.58) | SLC18A3DRD2SIGMAR1KCNH2HRH3 | |
| SCHEMBL27488566 | 0.78 | RIPK1 (0.51) | SLC18A3DRD2SIGMAR1KCNH2HRH3 | |
| SCHEMBL4198757 | 0.78 | NAMPT (0.65) | SLC18A3DRD2SIGMAR1KCNH2HRH3 | |
| SCHEMBL16393857 | 0.77 | SLC18A3 (0.48) | SLC18A3DRD2SIGMAR1KCNH2HRH3 | |
| SCHEMBL6245254 | 0.77 | NAMPT (0.64) | SLC18A3DRD2SIGMAR1KCNH2HRH3 | |
| SCHEMBL4976350 | 0.77 | SLC18A3 (0.60) | SLC18A3DRD2SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL29111290 | 0.76 | SLC18A3 (0.57) | SLC18A3SIGMAR1KCNH2HRH3ALDH1A1 | |
| SCHEMBL7380238 | 0.75 | ALDH1A1 (0.38) | SLC18A3ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL8528754 | 0.75 | SLC18A3 (0.46) | SLC18A3SIGMAR1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL27976831 | 0.75 | AKR1C3 (0.46) | SLC18A3SIGMAR1KCNH2HRH3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1649840-A | Non-peptidic BRS-3 agonists | SOLVAY PHARM GMBH (DE) | 2005-08-03 | — | — | CN | disclosed |