Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 11/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | SPR | P35270 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL381670 | 0.89 | MMP3 (0.50) | KCNH2HRH3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10006606 | 0.86 | MEN1 (0.39) | KCNH2NPC1RAB9AATMSMN1; SMN2 | |
| SCHEMBL27488566 | 0.84 | RIPK1 (0.51) | SLC18A3SIGMAR1KCNH2HRH3 | |
| SCHEMBL16755915 | 0.83 | CYP11B2 (0.48) | KCNH2SPR | |
| SCHEMBL942295 | 0.82 | EPHX2 (0.47) | HRH3CYP2C9 | |
| SCHEMBL27604008 | 0.81 | SLC18A3 (0.58) | SLC18A3SIGMAR1KCNH2HRH3CYP2D6 | |
| SCHEMBL29111290 | 0.79 | SLC18A3 (0.57) | SLC18A3SIGMAR1KCNH2HRH3NPC1 | |
| SCHEMBL9024555 | 0.79 | DRD4 (0.43) | SPR | |
| Hydrochloric Acid SCHEMBL27976831 | 0.78 | AKR1C3 (0.46) | SLC18A3SIGMAR1KCNH2HRH3NPC1 | |
| SCHEMBL571141 | 0.78 | KDM1A (0.60) | KCNH2HRH3NPC1RAB9AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648130-B1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | UNIV MICHIGAN (US) | 1998-12-30 | — | — | EP | disclosed |
| EP-0648130-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1995-04-19 | — | — | EP | disclosed |
| EP-0648130-A4 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING. | UNIV MICHIGAN (US) | 1994-01-26 | — | — | EP | disclosed |
| US-5077035-A | Scintigraphic imaging of brain; Alzheimer*s diagnosis | THE UNIVERSITY OF MICHIGAN (US) | 1991-12-31 | — | — | US | disclosed |
| WO-1991017776-A1 | RADIOIODINATED BENZOVESAMICOL ANALOGS FOR CHOLINERGIC NERVE MAPPING | THE UNIVERSITY OF MICHIGAN (US) | 1991-11-28 | — | — | WO | disclosed |