Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889256 | 0.90 | PTGER4 (0.48) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL27957318 | 0.90 | GAA (0.46) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL28415472 | 0.86 | ALDH1A1 (0.59) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL29120484 | 0.84 | EGFR (0.42) | GAACASP7CA1CA2CA9 | |
| SCHEMBL28757651 | 0.83 | NR3C2 (0.41) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL27622960 | 0.83 | NR3C2 (0.41) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL28932754 | 0.83 | KDM4E (0.44) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL28627930 | 0.83 | GAA (0.58) | KDM4EGAAALDH1A1HSD17B10GLA | |
| SCHEMBL28318092 | 0.81 | LMNA (0.57) | KDM4EALDH1A1HSD17B10GLAMAPT | |
| SCHEMBL27333283 | 0.80 | ALDH1A1 (0.35) | KDM4EGAAALDH1A1HSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1659161-A | Piperidine derivatives having CCR3 antagonism | TEIJIN LTD (JP) | 2005-08-24 | — | — | CN | disclosed |