Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62940 | 1.00 | MAPT (0.46) | MAPTALDH1A1HSD17B10CRBNDDB1 | |
| Alanine SCHEMBL6904183 | 0.85 | ALDH1A1 (0.36) | MAPTALDH1A1HSD17B10HTTTDP1 | |
| SCHEMBL1421444 | 0.81 | CRBN (0.41) | MAPTALDH1A1CRBNDDB1POLB | |
| SCHEMBL9864475 | 0.81 | MAPT (0.38) | MAPTALDH1A1HSD17B10CRBNDDB1 | |
| SCHEMBL9701179 | 0.80 | TDP2 (0.35) | MAPTALDH1A1HSD17B10KDM4ETDP1 | |
| SCHEMBL8899344 | 0.78 | KMT2A (0.41) | MAPTALDH1A1HSD17B10POLBMEN1 | |
| SCHEMBL22498758 | 0.73 | CRBN (0.35) | MAPTALDH1A1CRBNDDB1EPHX2 | |
| SCHEMBL9751662 | 0.73 | CRBN (0.35) | MAPTALDH1A1HSD17B10CRBNDDB1 | |
| SCHEMBL9751620 | 0.72 | CRBN (0.43) | MAPTALDH1A1HSD17B10CRBNDDB1 | |
| SCHEMBL8379436 | 0.70 | MEN1 (0.42) | MAPTALDH1A1HSD17B10CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1741810-A | Glycopeptide antibiotic derivatives | LEUVEN K U RES & DEV (BE) | 2006-03-01 | — | — | CN | disclosed |