Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | TOP2A | P11388 | 1/20 | 0.31 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62940 | 0.85 | MAPT (0.46) | ALDH1A1MAPTHSD17B10HTTMEN1 | |
| Benzene SCHEMBL27623239 | 0.85 | MAPT (0.46) | ALDH1A1MAPTHSD17B10HTTMEN1 | |
| Norleucine SCHEMBL7458261 | 0.83 | SLC1A2 (0.38) | MEN1KMT2ATDP1 | |
| Edetol SCHEMBL10909331 | 0.78 | RET (0.34) | ALDH1A1MAPTHSD17B10HTTKMT2A | |
| SCHEMBL27404604 | 0.76 | PTGS2 (0.39) | ALDH1A1MAPTHSD17B10MAOAMAOB | |
| SCHEMBL9701179 | 0.71 | TDP2 (0.35) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| Alanine SCHEMBL9768354 | 0.71 | CRBN (0.63) | ALDH1A1MAPTACETOP2ATOP2B | |
| Alanine SCHEMBL6904189 | 0.69 | GAA (0.45) | ALDH1A1MAPTHTTMEN1KMT2A | |
| SCHEMBL9864475 | 0.69 | MAPT (0.38) | ALDH1A1MAPTHSD17B10HTTMEN1 | |
| Oxindole SCHEMBL28451028 | 0.65 | AHR (0.66) | MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788305-B1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | UNIV COLUMBIA (US) | 2004-11-03 | — | — | EP | disclosed |
| US-6037386-A | LATEX BARRIER HAVING POLYMER MATRIX COMPRISING ZINC OXIDE OR ZINC GLUCONATE GEL IRRITANT DEACTIVATING AGENT; CONDOMS, GLOVES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-03-14 | — | — | US | disclosed |
| US-5965610-A | MIXTURE CONTAINING CHLORHEXIDINE GLUCONATE AND ZINC GLUCONATE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0788305-A4 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | UNIV COLUMBIA (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5708023-A | NONIRRITATING GEL FOR SKIN | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-01-13 | — | — | US | disclosed |
| EP-0788305-A1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | The Trustees of Columbia University in the City of New York (US) | 1997-08-13 | — | — | EP | disclosed |
| WO-1995026134-A1 | COMPOSITION FOR INACTIVATING IRRITANTS IN FLUIDS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1995-10-05 | — | — | WO | disclosed |