Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EGLN2 | Q96KS0 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072548 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAGAARAB9A | |
| SCHEMBL28145389 | 0.73 | BACE1 (0.47) | KDM4EALDH1A1RAB9ANOTUM | |
| SCHEMBL5776161 | 0.72 | CYP19A1 (0.40) | TSHRKDM4EALDH1A1GLAGAA | |
| SCHEMBL6221184 | 0.72 | RAB9A (0.44) | KDM4EALDH1A1GLAGAARAB9A | |
| SCHEMBL10148367 | 0.71 | ALDH1A1 (0.49) | TSHRKDM4EALDH1A1RAB9A | |
| SCHEMBL6225352 | 0.71 | RAB9A (0.43) | TSHRKDM4EALDH1A1GLAGAA | |
| Acetic Acid SCHEMBL27746838 | 0.70 | MAPT (0.43) | KDM4EALDH1A1RAB9A | |
| SCHEMBL6221632 | 0.70 | OPRD1 (0.38) | TSHRKDM4EALDH1A1GLAGAA | |
| SCHEMBL6219202 | 0.70 | KMT2A (0.42) | ALDH1A1RAB9ACYP11B2CYP11B1 | |
| SCHEMBL6226429 | 0.70 | ABCG2 (0.39) | TSHRKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1681813-A | Synthesis of indolizines | SYNTA PHARMACEUTICALS CORP (US) | 2005-10-12 | — | — | CN | disclosed |