SCHEMBL27623951

SCHEMBL27623951

CC(OCc1ccccc1)C(N)(C(=O)O)C(=O)OC(C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 2/20 0.44
SLC1A2 P43004 2/20 0.44
SLC1A1 P43005 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2D6 P10635 2/20 0.44
MEN1 O00255 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
PPARA Q07869 3/20 0.42
CTSS P25774 3/20 0.40
SYK P43405 1/20 0.39
PPARG P37231 2/20 0.38
LTA4H P09960 1/20 0.38
CTSL P07711 1/20 0.38
CTSB P07858 1/20 0.38
CTSK P43235 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
HIF1A Q16665 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11396394 0.81 SLC1A3 (0.47) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL4647195 0.78 ALDH1A1 (0.44) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL1536362 0.78 DGAT1 (0.32) CTSSCTSLCTSBCTSK
SCHEMBL28775488 0.77 SLC15A1 (0.46) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL2689315 0.76 SLC1A3 (0.46) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL16634782 0.76 FABP5 (0.45) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL7936496 0.76 PPARA (0.50) PPARACTSSSYKPPARGCTSL
SCHEMBL6064496 0.76 ALDH1A1 (0.50) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL6064499 0.76 ALDH1A1 (0.50) SLC1A3SLC1A2SLC1A1CYP1A2CYP2D6
SCHEMBL27703539 0.76 CYP1A2 (0.44) CYP1A2CYP2D6CYP2C19KMT2ACTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102267924-A Antibacterial agent 2011-12-07 CN disclosed
CN-1777577-B Antibacterial agent CHIRON CORP 2011-07-06 CN disclosed
CN-1777577-A Antibacterial agent CHIRON CORP (US) 2006-05-24 CN disclosed