SCHEMBL27625845

SCHEMBL27625845

Cc1c(N(N)C(N)=O)ccc(N(N)C(N)=O)c1C

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 8/20 0.34
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
MAPK1 P28482 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28063941 0.88 ALOX5 (0.30) ALOX5
SCHEMBL28085048 0.86 GAA (0.38) ALOX5GAAMAPTPARP1
SCHEMBL27762226 0.81
SCHEMBL28088811 0.77 TPMT (0.33) ALOX5PARP1
SCHEMBL27949173 0.77 MKNK1 (0.41) PARP1
SCHEMBL28084080 0.76 KCNN4 (0.31) PARP1
SCHEMBL27625976 0.76 ALOX5 (0.32) ALOX5MAPTPARP1
SCHEMBL29624292 0.76 SIGMAR1 (0.43) ALOX5GAAMAPTPARP1
SCHEMBL28172033 0.75 TSHR (0.40) ALOX5GAAMAPTMAPK1PARP1
SCHEMBL27896796 0.74 GAA (0.39) ALOX5GAAMAPTPARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101990406-A Air oxidation hair dye application system and method for dyeing hair using same COMBE INTERNAT LTD 2011-03-23 CN disclosed
CN-101616713-A Comprise the dyestuff that special anionic thickener is used for keratin fiber PROCTER & GAMBLE (US) 2009-12-30 CN disclosed
CN-101374495-A Colorant for keratin fibers PROCTER & GAMBLE (US) 2009-02-25 CN disclosed
CN-101312707-A Agent for colouring keratin fibres comprising 2-amino-5-methylphenol and m-aminophenol PROCTER & GAMBLE (US) 2008-11-26 CN disclosed
CN-101257886-A Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster PROCTER & GAMBLE (US) 2008-09-03 CN disclosed
CN-101065163-A Colouring agents containing cationic indazoline-thiazolazo dyes PROCTER & GAMBLE (US) 2007-10-31 CN disclosed
CN-101001600-A Multicomponent kit and method for dyeing keratin fibers WELLA AG (DE) 2007-07-18 CN disclosed
CN-1678285-A Dyeing method for porous material CIBA SC HOLDING AG (CH) 2005-10-05 CN disclosed