SCHEMBL27625976

SCHEMBL27625976

Cc1cc(N(N)C(N)=O)c(C)cc1N(N)C(N)=O

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 7/20 0.32
POLB P06746 1/20 0.31
PARP1 P09874 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27458729 0.90
SCHEMBL27999084 0.89
SCHEMBL27707933 0.84 POLB (0.33) ALOX5POLB
SCHEMBL27589730 0.84 MRGPRX4 (0.31)
SCHEMBL27949173 0.81 MKNK1 (0.41) PARP1TDP1
SCHEMBL27417120 0.80 MAPT (0.32) ALOX5MAPTTDP1
SCHEMBL27491377 0.80 KEAP1 (0.33) ALOX5POLBPARP1MAPTTDP1
SCHEMBL27604261 0.78 NNMT (0.33) TDP1
SCHEMBL28088811 0.77 TPMT (0.33) ALOX5PARP1
SCHEMBL27625845 0.76 ALOX5 (0.34) ALOX5PARP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101384303-B Coloring agent for coloring keratin fibers WELLA AG 2012-07-04 CN disclosed
CN-101990406-A Air oxidation hair dye application system and method for dyeing hair using same COMBE INTERNAT LTD 2011-03-23 CN disclosed
CN-1784457-B Imide-linked maleimide and polymaleimide compounds ADVANCED APPLIED ADHESIVES 2010-07-14 CN disclosed
CN-101616713-A Comprise the dyestuff that special anionic thickener is used for keratin fiber PROCTER & GAMBLE (US) 2009-12-30 CN disclosed
CN-101374495-A Colorant for keratin fibers PROCTER & GAMBLE (US) 2009-02-25 CN disclosed
CN-101312707-A Agent for colouring keratin fibres comprising 2-amino-5-methylphenol and m-aminophenol PROCTER & GAMBLE (US) 2008-11-26 CN disclosed
CN-101257886-A Agent for simultaneous lightening and coloring of keratin fibres containing a sulfamate bleach booster PROCTER & GAMBLE (US) 2008-09-03 CN disclosed
CN-101065163-A Colouring agents containing cationic indazoline-thiazolazo dyes PROCTER & GAMBLE (US) 2007-10-31 CN disclosed
CN-101001600-A Multicomponent kit and method for dyeing keratin fibers WELLA AG (DE) 2007-07-18 CN disclosed
CN-1678285-A Dyeing method for porous material CIBA SC HOLDING AG (CH) 2005-10-05 CN disclosed