Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27402173 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTGAAHTT | |
| SCHEMBL12368670 | 0.79 | ALOX15 (0.41) | SMN1; SMN2ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL27625946 | 0.75 | TYMP (0.55) | TYMPMEN1KMT2ACYP1A2 | |
| SCHEMBL29860930 | 0.72 | CYP1A2 (0.38) | ALDH1A1MAPTGAAHTTKDM4E | |
| SCHEMBL4767741 | 0.69 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL2632820 | 0.66 | YTHDF2 (0.52) | SMN1; SMN2ALDH1A1LMNAGAAHTT | |
| SCHEMBL10296643 | 0.66 | DAO (0.51) | MEN1KMT2ACYP1A2 | |
| SCHEMBL24420566 | 0.65 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL27816351 | 0.65 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1MAPTLMNAGAA | |
| SCHEMBL4618373 | 0.64 | KDM4E (0.46) | SMN1; SMN2ALDH1A1MAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003294-A | Gene fusion targeted therapy | UNIV MICHIGAN | 2013-03-27 | — | — | CN | disclosed |
| CN-101223269-B | Compositions and methods for treating tissue | CONJUGON INC | 2013-03-27 | — | — | CN | disclosed |
| CN-101341256-B | Recurrent gene fusions in prostate cancer | UNIV MICHIGAN | 2013-01-23 | — | — | CN | disclosed |
| CN-101014608-B | Methods and compositions for inhibiting gene expression | PRONAI THERAPEUTICS INC | 2011-07-06 | — | — | CN | disclosed |
| CN-101583624-A | Compositions and methods for diagnosing and treating cancer | ONCOMED PHARM INC (US) | 2009-11-18 | — | — | CN | disclosed |
| CN-101460634-A | Methods and compositions for targeting C-REL | CORNELL RES FOUNDATION INC (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101389758-A | Methods and compositions for modulating apoptotic pathways | UNIV NEW YORK (US) | 2009-03-18 | — | — | CN | disclosed |
| CN-101381725-A | Circular dumbbell decoy oligodeoxynucleotide (CDODN) containing transcription DNA binding sites | ANGES MG INC (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-101341256-A | Recurrent gene fusions in prostate cancer | UNIV MICHIGAN (US) | 2009-01-07 | — | — | CN | disclosed |
| CN-101223269-A | Compositions and methods for treating tissue | CONJUGON INC (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-1934255-A | Combination therapy for the treatment of ocular neovascular diseases | OSI EYETECH INC (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1910291-A | Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway | UNIV MICHIGAN (US) | 2007-02-07 | — | — | CN | disclosed |
| CN-1852974-A | Compositions and methods for treating and diagnosing cancer | UNIV MICHIGAN (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1688714-A | Diagnosis and treatment of the tuberous sclerosis pathway | UNIV MICHIGAN (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1665929-A | Circular dumbbell decoy oligodeoxynucleotides (CDODN) containing transcription DNA binding sites | ANGES MG INC (JP) | 2005-09-07 | — | — | CN | disclosed |