Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 15/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27625945 | 0.75 | SMN1; SMN2 (0.39) | TYMPMEN1KMT2ACYP1A2 | |
| SCHEMBL9535828 | 0.74 | TYMP (0.58) | TYMPATMMEN1KMT2A | |
| SCHEMBL29860930 | 0.72 | CYP1A2 (0.38) | MEN1KMT2ACYP1A2 | |
| SCHEMBL12368670 | 0.69 | ALOX15 (0.41) | MEN1KMT2ACYP1A2 | |
| SCHEMBL19148182 | 0.68 | SQOR (0.48) | TYMP | |
| SCHEMBL3654048 | 0.68 | MYC (0.41) | MEN1KMT2A | |
| SCHEMBL6027678 | 0.68 | TYMP (0.46) | TYMPATMMEN1KMT2A | |
| SCHEMBL10296643 | 0.66 | DAO (0.51) | MEN1KMT2ACYP1A2 | |
| SCHEMBL28380468 | 0.65 | TYMP (1.00) | TYMPATM | |
| SCHEMBL20998664 | 0.65 | TYMP (0.43) | TYMPATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003294-A | Gene fusion targeted therapy | UNIV MICHIGAN | 2013-03-27 | — | — | CN | disclosed |
| CN-101223269-B | Compositions and methods for treating tissue | CONJUGON INC | 2013-03-27 | — | — | CN | disclosed |
| CN-101341256-B | Recurrent gene fusions in prostate cancer | UNIV MICHIGAN | 2013-01-23 | — | — | CN | disclosed |
| CN-101014608-B | Methods and compositions for inhibiting gene expression | PRONAI THERAPEUTICS INC | 2011-07-06 | — | — | CN | disclosed |
| CN-101583624-A | Compositions and methods for diagnosing and treating cancer | ONCOMED PHARM INC (US) | 2009-11-18 | — | — | CN | disclosed |
| CN-101460634-A | Methods and compositions for targeting C-REL | CORNELL RES FOUNDATION INC (US) | 2009-06-17 | — | — | CN | disclosed |
| CN-101389758-A | Methods and compositions for modulating apoptotic pathways | UNIV NEW YORK (US) | 2009-03-18 | — | — | CN | disclosed |
| CN-101381725-A | Circular dumbbell decoy oligodeoxynucleotide (CDODN) containing transcription DNA binding sites | ANGES MG INC (JP) | 2009-03-11 | — | — | CN | disclosed |
| CN-101341256-A | Recurrent gene fusions in prostate cancer | UNIV MICHIGAN (US) | 2009-01-07 | — | — | CN | disclosed |
| CN-101223269-A | Compositions and methods for treating tissue | CONJUGON INC (US) | 2008-07-16 | — | — | CN | disclosed |
| CN-1934255-A | Combination therapy for the treatment of ocular neovascular diseases | OSI EYETECH INC (US) | 2007-03-21 | — | — | CN | disclosed |
| CN-1910291-A | Diagnosis and treatment of diseases arising from defects in the tuberous sclerosis pathway | UNIV MICHIGAN (US) | 2007-02-07 | — | — | CN | disclosed |
| CN-1852974-A | Compositions and methods for treating and diagnosing cancer | UNIV MICHIGAN (US) | 2006-10-25 | — | — | CN | disclosed |
| CN-1688714-A | Diagnosis and treatment of the tuberous sclerosis pathway | UNIV MICHIGAN (US) | 2005-10-26 | — | — | CN | disclosed |
| CN-1665929-A | Circular dumbbell decoy oligodeoxynucleotides (CDODN) containing transcription DNA binding sites | ANGES MG INC (JP) | 2005-09-07 | — | — | CN | disclosed |