Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27607641 | 0.86 | KMT2A (0.41) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL27626279 | 0.77 | KMT2A (0.48) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL1731751 | 0.75 | ADRA1D (0.39) | ADRA1DADRA1AADRA1BKMT2AMEN1 | |
| SCHEMBL27607663 | 0.75 | KMT2A (0.41) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL27626544 | 0.71 | KMT2A (0.40) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL27607658 | 0.70 | KMT2A (0.39) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL27626511 | 0.69 | EPHX2 (0.38) | KMT2AMEN1ALDH1A1KDM4ERECQL | |
| SCHEMBL27607616 | 0.69 | ALDH1A1 (0.36) | KMT2AMEN1ALDH1A1KDM4ERECQL | |
| Hydrochloric Acid SCHEMBL27626547 | 0.68 | KMT2A (0.44) | KMT2AMEN1ALDH1A1KDM4EPOLB | |
| SCHEMBL2895893 | 0.65 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646508-A | 5-substituted 1, 1-dioxo-1, 2, 5-thiadiazolidin-3-one derivatives as PTP-1B inhibitors | NOVARTIS AG (CH) | 2005-07-27 | — | — | CN | disclosed |