Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28907645 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL30293099 | 0.82 | TSHR (0.61) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL195278 | 0.81 | TSHR (0.75) | ALDH1A1HSD17B10TSHRKMT2ARAB9A | |
| SCHEMBL29619268 | 0.81 | TSHR (0.75) | ALDH1A1HSD17B10TSHRKMT2ARAB9A | |
| SCHEMBL4734723 | 0.78 | TSHR (0.54) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL27607912 | 0.77 | AKR1C3 (0.59) | ALDH1A1HSD17B10KMT2AMAPTGAA | |
| SCHEMBL13356584 | 0.77 | TSHR (0.62) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL5609240 | 0.77 | TSHR (0.58) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL28664625 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRHPGDKMT2A | |
| SCHEMBL10385659 | 0.77 | TSHR (0.53) | ALDH1A1HSD17B10TSHRHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1683303-A | Novel use of 3,4-dihydroxy-benzene formaldehyde and its derivatives in treating hypatitis B and virus infectious diseases | INST OF RADIATION AND IRRADIAT (CN) | 2005-10-19 | — | — | CN | disclosed |