Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733091 | 0.87 | TSHR (0.53) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL195278 | 0.85 | TSHR (0.75) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL29619268 | 0.85 | TSHR (0.75) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL28552669 | 0.85 | TSHR (0.56) | TSHRALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL5609240 | 0.84 | TSHR (0.58) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL301748 | 0.84 | TSHR (0.64) | TSHRALDH1A1NPC1SMN1; SMN2GLA | |
| SCHEMBL28384878 | 0.84 | AKR1C3 (0.61) | NPC1SMN1; SMN2NPSR1POLBKDM4E | |
| SCHEMBL27849440 | 0.83 | AKR1C3 (0.50) | ALDH1A1NPC1SMN1; SMN2NPSR1RAB9A | |
| SCHEMBL4463486 | 0.83 | TSHR (0.70) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 | |
| SCHEMBL3947568 | 0.82 | POLB (0.65) | TSHRALDH1A1NPC1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008060844-A1 | POLYMERIZATION INHIBITOR COMPOSITIONS, THEIR PREPARATION, AND THEIR USE | ALBEMARLE CORPORATION (US) | 2008-05-22 | — | — | WO | disclosed |