Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | GLI1 | P08151 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363208 | 0.78 | — | — | |
| SCHEMBL23166480 | 0.75 | — | — | |
| SCHEMBL2540271 | 0.74 | — | — | |
| SCHEMBL2536727 | 0.74 | — | — | |
| SCHEMBL2536402 | 0.73 | CHRNB2 (0.40) | SLC6A2CHRM3 | |
| SCHEMBL2538623 | 0.70 | SLC6A2 (0.35) | SLC6A4SLC6A2SLC6A3GLI1 | |
| SCHEMBL2542483 | 0.69 | GLI1 (0.37) | GLI1 | |
| SCHEMBL2536297 | 0.69 | — | — | |
| SCHEMBL2541562 | 0.69 | — | — | |
| SCHEMBL27670508 | 0.69 | MAPK1 (0.37) | SLC6A4SLC6A2SLC6A3CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812981-A | Heteroaryloxy nitrogenous saturated heterocyclic derivative | BANYU PHARMA CO LTD (JP) | 2006-08-02 | — | — | CN | disclosed |