⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166480 | 0.80 | — | — | |
| SCHEMBL2536727 | 0.78 | — | — | |
| SCHEMBL27627003 | 0.78 | SLC6A4 (0.36) | — | |
| SCHEMBL2536402 | 0.78 | CHRNB2 (0.40) | — | |
| SCHEMBL27670508 | 0.74 | MAPK1 (0.37) | — | |
| SCHEMBL28058416 | 0.71 | — | — | |
| SCHEMBL9496924 | 0.70 | — | — | |
| SCHEMBL2048361 | 0.66 | — | — | |
| SCHEMBL910478 | 0.64 | — | — | |
| SCHEMBL20276630 | 0.64 | SLC6A1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1898234-A | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORP (US) | 2007-01-17 | — | — | CN | claimed |
| CN-104080769-A | Aryl or heteroaryl substituted benzene compounds | EPIZYME INC | 2014-10-01 | — | — | CN | disclosed |
| CN-1898234-A | Substituted cyclic hydroxamates as inhibitors of matrix metalloproteinases | INCYTE CORP (US) | 2007-01-17 | — | — | CN | disclosed |
| CN-1062143-A | Condensed heterocyclic compouds and preparation thereof and application | TAKADA CHEMIEAL IND LTD (JP) | 1992-06-24 | — | — | CN | disclosed |