SCHEMBL2762802

SCHEMBL2762802

O=C(O)c1c(C(=O)O)c(C(=O)O)c(C(=O)OC(=O)c2c(C(=O)O)c(C(=O)O)c(C(=O)O)c(C(=O)O)c2C(=O)O)c(C(=O)O)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.36
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 2/20 0.33
CA9 Q16790 2/20 0.33
CA14 Q9ULX7 2/20 0.33
ALDH1A1 P00352 2/20 0.30
KDM4E B2RXH2 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28049565 1.00 CYP1A2 (0.36) CYP1A2CA12CA1CA2CA7
SCHEMBL27788667 0.97 CYP1A2 (0.35) CYP1A2CA12CA1CA2CA7
SCHEMBL28210324 0.97 CYP1A2 (0.35) CYP1A2CA12CA1CA2CA7
SCHEMBL9116152 0.88 CYP1A2 (0.33) CYP1A2CA12CA1CA2CA7
SCHEMBL27279772 0.87 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL27526066 0.87 CA12 (0.43) CA12CA1CA2CA7CA9
SCHEMBL27871138 0.87 ALDH1A1 (0.43) CA12CA1CA2CA7CA9
SCHEMBL17385578 0.84 POLB (0.34) CYP1A2CA12CA1CA2CA7
SCHEMBL7927764 0.84 TSHR (0.43) CA12CA1CA2CA7CA9
Mellitic Acid SCHEMBL27648413 0.83 ALDH1A1 (0.45) CYP1A2CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7662801-B2 Biodegradable oxidized cellulose esters UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2010-02-16 US disclosed
US-7649089-B2 Prepared by reacting oxidized cellulose ethers with alcohol in presence of carbodiimide coupling agent, and basic catalyst such as 4-(dimethylamino) pyridine (DMAP); emulsification; for use as binder, filler, and/or disintegrant in development of solid dosage forms; controlled release UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2010-01-19 US disclosed
US-7595392-B2 Cellulose ether for use in drug delivery in veterinary medicine UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2009-09-29 US disclosed
US-20060093672-A1 Biodegradable oxidized cellulose esters UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2006-05-04 US disclosed
US-20050131225-A1 Biodegradable oxidized cellulose esters and their uses as microspheres UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-06-16 US disclosed
WO-2005047339-A1 BIODEGRADABLE OXIDIZED CELLULOSE ESTERS AND THEIR USES AS MICROSPHERES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2005-05-26 WO disclosed
WO-2002053599-A2 BIODEGRADABLE OXIDIZED CELLULOSE ESTERS UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2002-07-11 WO disclosed
US-20020086990-A1 Biodegradable oxidized cellulose esters UNIVERSITY OF IOWA RESEARCH FOUNDATION 2002-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060093672-A1 Biodegradable oxidized cellulose esters CS, OTC, ACMSD CYP1A2 97/4885CA12 980/4885CA1 1433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.