Orthocresol

Orthocresol

SCHEMBL27628632

C.Cc1ccccc1O.c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.55
ATM Q13315 1/20 0.55
ALDH1A1 P00352 6/20 0.50
LMNA P02545 4/20 0.50
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
HPGD P15428 3/20 0.50
HSD17B10 Q99714 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
NPC1 O15118 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.50
CA12 O43570 1/20 0.50
GMNN O75496 1/20 0.50
EGFR P00533 1/20 0.50
CA2 P00918 1/20 0.50
FYN P06241 1/20 0.50
POLB P06746 1/20 0.50
CA3 P07451 1/20 0.50
CYP3A4 P08684 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Orthocresol SCHEMBL3862455 0.97 TRPA1 (0.57) TRPA1ATMALDH1A1LMNAKDM4E
Orthocresol SCHEMBL27617530 0.97
Orthocresol SCHEMBL170162 0.94 TRPA1 (0.60) TRPA1ATMALDH1A1LMNAKDM4E
Orthocresol SCHEMBL8710164 0.94 TRPA1 (0.60) TRPA1ATMALDH1A1LMNAKDM4E
Orthocresol SCHEMBL16002 0.94
Orthocresol SCHEMBL10419161 0.94 TRPA1 (0.60) TRPA1ATMALDH1A1LMNAKDM4E
Orthocresol SCHEMBL29395276 0.94
Orthocresol SCHEMBL6227970 0.91
Orthocresol SCHEMBL2210412 0.91 ALDH1A1 (0.62) TRPA1ATMALDH1A1LMNAKDM4E
Orthocresol SCHEMBL2840111 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1769344-A Thermosetting resin composition, and prepreg, metal-clad laminated board and printed wiring board using the same HITACHI CHEMICAL CO LTD (JP) 2006-05-10 CN disclosed