Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5541257 | 0.91 | LMNA (0.39) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL5535404 | 0.91 | LMNA (0.39) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL5535399 | 0.91 | LMNA (0.39) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL5542523 | 0.88 | ALDH1A1 (0.41) | LMNAKMT2AALDH1A1KCNH2POLB | |
| SCHEMBL5543424 | 0.84 | LMNA (0.34) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL5546200 | 0.84 | ACHE (0.37) | LMNAKMT2AALDH1A1MITFKDM4E | |
| SCHEMBL5546190 | 0.84 | ACHE (0.37) | LMNAKMT2AALDH1A1MITFKDM4E | |
| SCHEMBL5543414 | 0.84 | LMNA (0.34) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL27610573 | 0.80 | KMT2A (0.40) | LMNAKMT2AALDH1A1MITFPKM | |
| SCHEMBL6010609 | 0.79 | ALDH1A1 (0.43) | LMNAKMT2AALDH1A1KCNH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101255170-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-09-03 | — | — | CN | disclosed |
| CN-101172981-A | 2,3-dihydroimidazo[2,1-b]oxazole compound | OTSUKA PHARMA CO LTD (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100366624-C | 2, 3-dihydro-6-nitroimidazo [2,1-b ] * azole compounds | OTSUKA PHARMA CO LTD (JP) | 2008-02-06 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |