Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.51 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2096009 | 0.88 | MTNR1A (0.49) | MTNR1AMTNR1BSLC6A4LMNAGAA | |
| SCHEMBL2092589 | 0.87 | MTNR1A (0.55) | MTNR1AMTNR1BSLC6A4LMNAGAA | |
| SCHEMBL7973526 | 0.82 | MTNR1A (0.53) | MTNR1AMTNR1BSLC6A4LMNAALDH1A1 | |
| SCHEMBL1454240 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BSLC6A4LMNAMAPT | |
| SCHEMBL7582723 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BSLC6A4LMNALTA4H | |
| SCHEMBL4665496 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1BSLC6A4LMNAGAA | |
| SCHEMBL331604 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BSLC6A4LMNAGAA | |
| SCHEMBL7404204 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BSLC6A4LMNACYP1A2 | |
| SCHEMBL218384 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1BSLC6A4LMNAGAA | |
| SCHEMBL11502513 | 0.79 | MTNR1A (0.56) | MTNR1AMTNR1BGAACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |