SCHEMBL7404204

SCHEMBL7404204

CC(CCCl)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
SLC6A4 P31645 2/20 0.41
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TSHR P16473 2/20 0.38
SLC22A2 O15244 1/20 0.38
SLC22A1 O15245 1/20 0.38
SLC22A3 O75751 1/20 0.38
ESR1 P03372 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD2 P14416 1/20 0.38
ADRA2B P18089 1/20 0.38
ADRA2C P18825 1/20 0.38
CHRM3 P20309 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9674388 0.83 MTNR1A (0.50) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL1454240 0.81 MTNR1A (0.49) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL27629520 0.79 MTNR1A (0.51) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL7582723 0.79 MTNR1A (0.47) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL218384 0.79 MTNR1A (0.47) MTNR1AMTNR1BSLC6A4LMNAADRA2A
SCHEMBL4665496 0.79 MTNR1A (0.51) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL331604 0.79 MTNR1A (0.47) MTNR1AMTNR1BSLC6A4LMNAADRA2A
SCHEMBL2092589 0.78 MTNR1A (0.55) MTNR1AMTNR1BSLC6A4LMNAALDH1A1
SCHEMBL9870637 0.78 MTNR1A (0.53) MTNR1AMTNR1BSLC6A4LMNATSHR
SCHEMBL9870647 0.78 MTNR1A (0.53) MTNR1AMTNR1BSLC6A4LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0869792-A4 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER LAMBERT CO (US) 1999-09-22 EP disclosed
EP-0869792-A2 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1998-10-14 EP disclosed
WO-1997023216-A1 4-SUBSTITUTED PIPERIDINE ANALOGS AND THEIR USE AS SUBTYPE SELECTIVE NMDA RECEPTOR ANTAGONISTS WARNER-LAMBERT COMPANY (US) 1997-07-03 WO disclosed