Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27629520 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BSLC6A4ALDH1A1LMNA | |
| SCHEMBL7973530 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9869716 | 0.79 | MTNR1A (0.55) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11759003 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL9888683 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL18754954 | 0.77 | MTNR1A (0.53) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL7170118 | 0.75 | PDE4B (0.55) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL10899564 | 0.75 | MTNR1A (0.51) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL11127176 | 0.75 | MTNR1A (0.56) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL418159 | 0.73 | CYP2C9 (0.52) | MTNR1AMTNR1BTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |