Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.74 |
| ▸ | FYN | P06241 | 6/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630135 | 0.92 | MET (0.64) | METFYNMAP4K4JAK2MAP4K3 | |
| SCHEMBL27629924 | 0.87 | MET (0.56) | METFYNMAP4K4MPOCSF1R | |
| SCHEMBL487777 | 0.86 | MET (0.83) | METFYNMAP4K4MPOCSF1R | |
| SCHEMBL487830 | 0.85 | MET (1.00) | METFYNMAP4K4MPOMAP4K3 | |
| SCHEMBL30453987 | 0.85 | MET (1.00) | METFYNMAP4K4MPOMAP4K3 | |
| SCHEMBL487907 | 0.85 | MET (0.81) | METFYNMAP4K4MPOCSF1R | |
| SCHEMBL487956 | 0.84 | MET (0.76) | METFYNMAP4K4MPOMAP4K3 | |
| SCHEMBL488042 | 0.84 | MET (0.79) | METFYNMAP4K4MPOJAK2 | |
| Water SCHEMBL28121971 | 0.84 | MET (0.79) | METFYNMAP4K4MPOCSF1R | |
| SCHEMBL27630181 | 0.83 | MET (0.51) | METFYNMAP4K4PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |