Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630129 | 0.92 | MET (0.74) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL27630181 | 0.87 | MET (0.51) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL487969 | 0.87 | MET (0.84) | METMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL30453384 | 0.87 | MET (0.84) | METMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL488145 | 0.87 | MET (0.68) | METMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27629924 | 0.82 | MET (0.56) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL30454009 | 0.82 | MET (0.65) | METSMN1; SMN2MAP4K4 | |
| SCHEMBL487893 | 0.82 | MET (0.65) | METSMN1; SMN2MAP4K4 | |
| SCHEMBL488042 | 0.82 | MET (0.79) | METJAK2MAP4K3FYNMAP4K4 | |
| SCHEMBL27630151 | 0.81 | MET (0.48) | METRAB9AJAK2MAP4K3FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |