Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.75 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.53 |
| ▸ | USP7 | Q93009 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 3/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452824 | 1.00 | MET (0.75) | METMAP4K3MAP4K4USP7GAA | |
| SCHEMBL487657 | 1.00 | MET (0.75) | METMAP4K3MAP4K4USP7GAA | |
| SCHEMBL488082 | 0.91 | MET (0.61) | METMAP4K3MAP4K4USP7MPO | |
| SCHEMBL27630243 | 0.89 | MET (0.61) | METMAP4K3MAP4K4USP7MPO | |
| SCHEMBL30453912 | 0.87 | MET (0.57) | METMAP4K3MAP4K4USP7MPO | |
| SCHEMBL488210 | 0.87 | MET (0.57) | METMAP4K3MAP4K4USP7MPO | |
| SCHEMBL487832 | 0.87 | MAP4K4 (0.73) | METMAP4K3MAP4K4MCL1 | |
| SCHEMBL30454971 | 0.87 | MAP4K4 (0.73) | METMAP4K3MAP4K4MCL1 | |
| SCHEMBL30453337 | 0.86 | MET (0.66) | METMAP4K3MAP4K4USP7GAA | |
| SCHEMBL487769 | 0.86 | MET (0.66) | METMAP4K3MAP4K4USP7GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |