Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.66 |
| ▸ | INPPL1 | O15357 | 4/20 | 0.53 |
| ▸ | USP7 | Q93009 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.45 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.45 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL487769 | 1.00 | MET (0.66) | METINPPL1USP7MAP4K4FYN | |
| SCHEMBL487782 | 0.89 | MET (0.65) | METINPPL1USP7MAP4K4FYN | |
| SCHEMBL30453255 | 0.89 | MET (0.65) | METINPPL1USP7MAP4K4FYN | |
| SCHEMBL30454350 | 0.87 | MAP4K4 (0.65) | METINPPL1MAP4K4 | |
| SCHEMBL487663 | 0.87 | MAP4K4 (0.65) | METINPPL1MAP4K4 | |
| SCHEMBL487657 | 0.86 | MET (0.75) | METUSP7MAP4K4FYNMAP4K3 | |
| SCHEMBL30452824 | 0.86 | MET (0.75) | METUSP7MAP4K4FYNMAP4K3 | |
| SCHEMBL27630242 | 0.86 | MET (0.75) | METUSP7MAP4K4FYNMAP4K3 | |
| SCHEMBL27650116 | 0.86 | MET (0.51) | METINPPL1MAP4K4FYNMAP4K3 | |
| SCHEMBL27629915 | 0.81 | MET (0.59) | METINPPL1MAP4K4MAP4K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |