Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.57 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.56 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.47 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL488210 | 1.00 | MET (0.57) | METMAP4K3INPPL1MPOMAP4K4 | |
| SCHEMBL488082 | 0.88 | MET (0.61) | METMAP4K3MPOMAP4K4CSF1R | |
| SCHEMBL27630242 | 0.87 | MET (0.75) | METMAP4K3MPOMAP4K4USP7 | |
| SCHEMBL30452824 | 0.87 | MET (0.75) | METMAP4K3MPOMAP4K4USP7 | |
| SCHEMBL487657 | 0.87 | MET (0.75) | METMAP4K3MPOMAP4K4USP7 | |
| SCHEMBL30454638 | 0.86 | MET (0.77) | METMAP4K3INPPL1MPOMAP4K4 | |
| SCHEMBL488258 | 0.86 | MET (0.77) | METMAP4K3INPPL1MPOMAP4K4 | |
| SCHEMBL30454968 | 0.85 | MAP4K3 (0.54) | METMAP4K3INPPL1MPOMAP4K4 | |
| SCHEMBL488416 | 0.85 | MAP4K3 (0.54) | METMAP4K3INPPL1MPOMAP4K4 | |
| SCHEMBL488108 | 0.85 | MAP4K3 (0.56) | METMAP4K3INPPL1MPOMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113181362-B | Medicament for preventing and/or treating amyotrophic lateral sclerosis | 国立大学法人京都大学 | 2023-06-13 | — | — | CN | disclosed |