Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | IL2 | P60568 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.49 |
| ▸ | APOB | P04114 | 2/20 | 0.48 |
| ▸ | MTTP | P55157 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086631 | 0.89 | NPC1 (0.54) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7133291 | 0.88 | NPC1 (0.56) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7086952 | 0.87 | PLG (0.53) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7087379 | 0.85 | RXFP1 (0.57) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL6791178 | 0.85 | PTGS1 (0.67) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7079806 | 0.84 | NPC1 (0.49) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7083755 | 0.84 | RXFP1 (0.56) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7079790 | 0.84 | S1PR1 (0.51) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 | |
| SCHEMBL7084242 | 0.82 | MAPT (0.58) | MTTP | |
| SCHEMBL7079529 | 0.82 | MCHR1 (0.48) | PTGS1NPC1RAB9ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | PTGS1 1382/4885NPC1 64/4885RAB9A 3707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.