Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT3 | O60678 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870960 | 0.87 | PRMT3 (0.53) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL27492 | 0.85 | — | — | |
| SCHEMBL13316311 | 0.84 | ADRA1D (0.47) | PRMT3CARM1PRMT6PRMT1PRMT8 | |
| Ammonia Solution, Strong SCHEMBL7288994 | 0.83 | — | — | |
| SCHEMBL28627062 | 0.83 | — | — | |
| SCHEMBL12125006 | 0.83 | — | — | |
| SCHEMBL11470279 | 0.83 | — | — | |
| SCHEMBL7254828 | 0.82 | SLC18A3 (0.43) | — | |
| SCHEMBL11498988 | 0.82 | — | — | |
| SCHEMBL5888793 | 0.82 | OPRD1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100386323-C | Synthesis of domperidone maleate | NANJING CHANG AO MEDICINE SCI (CN) | 2008-05-07 | — | — | CN | disclosed |
| CN-1810805-A | Synthesis of domperidone maleate | NANJING CHANG AO MEDICINE SCI (CN) | 2006-08-02 | — | — | CN | disclosed |