Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630417 | 0.77 | KDM4E (0.33) | CDK5CDK5R1PDE2AALDH1A1KDM4E | |
| SCHEMBL6705449 | 0.73 | KDM4E (0.33) | PDE2AALDH1A1KDM4EHPGDADRA1A | |
| SCHEMBL6151952 | 0.69 | KDM4E (0.59) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL27725381 | 0.63 | HSP90AA1 (0.39) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL15432438 | 0.63 | ALDH1A1 (0.42) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL9584563 | 0.62 | HDAC6 (0.41) | — | |
| SCHEMBL23471177 | 0.59 | ALDH1A1 (0.38) | ALDH1A1TDP1HSD17B10 | |
| SCHEMBL9583170 | 0.59 | CDK1 (0.47) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL10996278 | 0.58 | HSD17B10 (0.54) | ALDH1A1KDM4EHPGDADRA1AHSD17B10 | |
| SCHEMBL6365879 | 0.58 | HSP90AB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1812990-A | Process for the preparation of famciclovir | TEVA PHARMA (IL) | 2006-08-02 | — | — | CN | disclosed |