Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | PDE8A | O60658 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 2/20 | 0.30 |
| ▸ | CDK2 | P24941 | 2/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | PRKACG | P22612 | 1/20 | 0.30 |
| ▸ | PRKACB | P22694 | 1/20 | 0.30 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630417 | 0.85 | KDM4E (0.33) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL8369323 | 0.76 | KDM4E (0.55) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL6151952 | 0.73 | KDM4E (0.59) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27630360 | 0.73 | CDK5 (0.33) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27725381 | 0.70 | HSP90AA1 (0.39) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL28434898 | 0.63 | KDM4E (0.54) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL9584563 | 0.61 | HDAC6 (0.41) | CDK1CDK2PRKACACCNA2PRKACG | |
| SCHEMBL24790521 | 0.60 | CDK1 (0.44) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL10922755 | 0.59 | HSP90AB1 (0.43) | KDM4EALDH1A1HPGDADRA1AHSD17B10 | |
| SCHEMBL27620345 | 0.59 | CDK1 (0.46) | KDM4EALDH1A1HPGDADRA1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040266795-A1 | Process for the preparation of famciclovir | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-12-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266795-A1 | Process for the preparation of famciclovir | ADH1C, CPS1, PAICS | KDM4E 114/4885ALDH1A1 186/4885HPGD 3258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.