Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL722560 | 0.89 | RAB9A (0.59) | PLA2G7MEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL6833454 | 0.87 | RAB9A (0.57) | PLA2G7MEN1KMT2AALDH1A1TDP1 | |
| Bromide SCHEMBL7502411 | 0.87 | RAB9A (0.57) | PLA2G7MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL10625612 | 0.81 | PLA2G7 (0.51) | PLA2G7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL28474122 | 0.80 | PLA2G7 (0.60) | PLA2G7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL14881017 | 0.78 | MEN1 (0.54) | PLA2G7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL899534 | 0.78 | SMN1; SMN2 (0.61) | PLA2G7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL2981886 | 0.78 | ALDH1A1 (0.61) | PLA2G7MEN1KMT2APOLBALDH1A1 | |
| SCHEMBL3053636 | 0.78 | SYK (0.54) | PLA2G7MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL5762561 | 0.78 | PLA2G7 (0.58) | PLA2G7MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1780823-A | Heteroaromatic pentacyclic compound and medicinal use thereof | JAPAN TOBACCO INC (JP) | 2006-05-31 | — | — | CN | disclosed |