Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 2/20 | 0.49 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CTSK | P43235 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630641 | 1.00 | ECE1 (0.49) | ECE1RENBACE1KMT2AAPP | |
| SCHEMBL19384891 | 0.96 | REN (0.49) | ECE1RENBACE1KMT2AAPP | |
| SCHEMBL20677180 | 0.96 | REN (0.49) | ECE1RENBACE1KMT2AAPP | |
| SCHEMBL20677179 | 0.96 | REN (0.49) | ECE1RENBACE1KMT2AAPP | |
| SCHEMBL3493240 | 0.90 | BACE1 (0.52) | RENBACE1APPCTSSCTSK | |
| SCHEMBL30186037 | 0.89 | KMT2A (0.46) | RENKMT2ACTSSCTSKCTSL | |
| SCHEMBL29918245 | 0.87 | REN (0.44) | RENBACE1KMT2ACTSSCTSK | |
| SCHEMBL29274070 | 0.87 | KMT2A (0.47) | RENKMT2ACTSSCTSKCTSL | |
| SCHEMBL29274069 | 0.87 | KMT2A (0.47) | RENKMT2ACTSSCTSKCTSL | |
| SCHEMBL999894 | 0.87 | APP (0.49) | ECE1APPCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100381459-C | Adriamycin derivative and its preparing method and use | CHENGDU NANSHAN PHARMACEUTICAL (CN) | 2008-04-16 | — | — | CN | disclosed |
| CN-1781932-A | Adriamycin derivative and its preparing method and use | NANSHAN PHARMACEUTICAL CO LTD (CN) | 2006-06-07 | — | — | CN | disclosed |